Currently, pathogenic microorganisms are IDed on “post culture positive” samples via their phenotype. The process involves growth on a blood-agar plate to isolate the organism, creation of a suspension of bacteria, and running a series of reactions to test for the production/consumption of specific proteins/enzymes. Each one of these reactions are specific to certain types of bacteria. The process can take over 24 hours. Because they are run on blood culture positive samples, the final results are too slow to impact patient care.
Some newer tests provide for faster ID of the bacteria (via rapid PCR tests) or faster ID and AST via microscopic observations of growth. But even so, these faster test results come in about 12 hours after the blood culture positive, and have a marginal impact on patient outcomes. And they are very expensive.
Our BloodFAST test provides for rapid ID and AST of the blood culture positive samples in 2.5 hours, and is relatively inexpensive compared to the PCR type tests. The test identifies most of the commonly observed bacteria in bloodsteam infections (covering about >95% of all cases), and provides AST information against a panel of 22 candidate antimicrobials.